Protein Degraders & Molecular Glues Icon

Cambridge Healthtech Institute’s 6th Annual

Protein Degraders & Molecular Glues - Part 2

Emerging Degrader Modalities and Screening Strategies

APRIL 12 - 13, 2023


The ubiquitin-proteasome, lysosome, and autophagy systems are all well-controlled, selective pathways for intracellular protein degradation and turnover, and act as key regulators in cancer, CNS, and other diseases. However, a new generation of inhibitors and activators are now being developed to disrupt protein-protein interactions and hijack these systems for targeted protein degradation or stabilization. Using this strategy, Proteolysis-targeting chimeras (PROTACs), molecular glues, and other small molecule modalities are being used to seek out previously “undruggable” targets for therapeutic intervention. However, challenges do exist in terms of specificity, stability, biodistribution, and penetration of these degrader molecules. This two-part conference on Protein Degraders & Molecular Glues brings together experts in the field to discuss important issues underlying the use of targeted protein degradation as a new therapeutic approach.

Please click here to return to the agenda for Protein Degraders & Molecular Glues - Part 1

For more details on the conference, please contact:

Tanuja Koppal, PhD

Senior Conference Director

Cambridge Healthtech Institute



For sponsorship information, please contact:

Kristin Skahan

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5431