Cambridge Healthtech Institute’s 2nd Annual
Covalent Modifications & Induced Proximity
Innovative Chemistries and Strategies Driving Covalent Drug Discovery
APRIL 10, 2023 | 1:00PM-5:15PM PDT
Proximity is critical for certain biological interactions and in post-translational modifications such as, ubiquitination, phosphorylation, methylation, and acetylation. Chemically induced proximity is an emerging area of interest where covalent chemistries
are being utilized to induce proximity to trigger biological processes such as protein degradation, protein stabilization, protein folding, chromatin regulation, and more. This symposium on Covalent Modifications & Induced Proximity brings together
academic and industry scientists from medicinal chemistry, chemical biology, and proteomics groups to discuss the innovative chemistries and technologies that can be leveraged to induce proximity for mechanistic studies, as well as for therapeutic
intervention.