Cambridge Healthtech Institute’s 3rd Annual
Covalent Modifications & Induced Proximity
Innovative Chemistries and Assays for Studying and Modulating Cellular Interactions
APRIL 1, 2024 | 1:00-5:00 PM
Proximity is critical for certain biological interactions and in post-translational modifications (PTMs) such as ubiquitination, phosphorylation, methylation, and acetylation. Chemically induced proximity is an emerging area of interest where covalent chemistries are being utilized for protein degradation, stabilization, folding, and more. This symposium on Covalent Modifications & Induced Proximity brings together academic and industry scientists from medicinal chemistry, chemical biology, and proteomics groups to discuss how innovative chemistries and technologies can be leveraged to induce proximity for mechanistic studies, as well as for therapeutic intervention. It offers a preview of the topics that will be discussed in the conferences on Degraders & Molecular Glues and Protein-Protein Interactions that follow.