Covalent Modifications and Induced Proximity Icon

Cambridge Healthtech Institute’s Inaugural

Covalent Modifications & Induced Proximity

April 18, 2022


Proximity is critical for some biological interactions and plays a role in post-translational modifications such as ubiquitination, phosphorylation, methylation, acetylation. Chemically induced proximity is an emerging area of interest where covalent chemistries are being utilized to modulate biological processes such as protein degradation, protein stabilization, protein folding, chromatin regulation and more. This inaugural symposium on Covalent Modifications & Induced Proximity brings together academic and industry scientists from medicinal chemistry, chemical biology and proteomics groups to discuss the innovative chemistries and technologies being developed to leverage induced proximity for mechanistic studies and for possible therapeutic intervention.


Coverage will likely include:


  • Utilizing innovative covalent chemistries for inducing proximity
  • Case studies highlighting role of induced proximity in initiating cellular changes
  • Advances in tools for modeling and characterizing chemically induced proximity
  • Use of proximity inducers for dissecting kinetics and mechanisms of cellular pathways
  • Emerging use of small molecule induced proximity for designing new drugs
  • Induced proximity using small molecule protein degraders and stabilizers


If you would like to submit a proposal to give a presentation at this meeting, please click here.


The deadline for priority consideration is October 1, 2021.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


We hope you can join us for this afternoon symposium during the first day of our 17th Annual Drug Discovery Chemistry event. Add on to your registration and attend the main event starting the next day. With two sets of 5+4 parallel conferences, you can also move back and forth to create your own agenda, whether you join in person or virtually.


For more details on the conference, please contact:

Tanuja Koppal, PhD

Senior Conference Director

Cambridge Healthtech Institute



For partnering and sponsorship information, please contact:

Aimee Croke
Business Development Manager
Cambridge Healthtech Institute
Phone: (+1) 781-972-5458